NES
May 1st – Exerion (Jaleco)
May 1st – Super Mario Bros. 2 (Nintendo)
May 2007 – Tsuppari Oozumou (Tecmo)
May 2007 – Challenger (Tecmo)

Nintendo 64
May 2007 – F-Zero X (Nintendo)

Genesis
May 2007 – Bare Knuckle II: Shitou no Chinkon Uta [Streets of Rage II] (Sega)
May 2007 – Chameleon Kid (Sega)
May 2007 – Shining in the Darkness (Sega)
May 2007 – The Hybrid Front (Sega)

TG16
May 1st – Neutopia (Hudson)
May 2007 – Saigo no Nindou: Ninja Spirit (Irem)
May 2007 – Out Live (SunSoft)
May 2007 – Sengoku Mahjong (Hudson)
May 2007 – Chou Zetsurinjin Beraboh Man (Bandai Namco)
May 2007 – PC Genjin 3 (Hudson)
May 2007 – Battle Lode Runner (Hudson)

Source: gamefront